Innovative Therapies and Clinical Studies for Screenable Disorders (R01)

Purpose. This Funding Opportunity Announcement (FOA) issued by the National Institute of Child Health and Human Development (NICHD), the National Institute on Deafness and Other Communication Disorders (NIDCD), and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), solicit applications for research relevant to the basic understanding and development of therapeutic interventions for currently screened conditions and high priority genetic conditions for which screening could be possible in the near future. In this FOA, a high priority condition is a condition for which the development of an efficacious therapy would make the condition amenable to newborn screening. Mechanism of Support. This FOA will use the NIH Research Project Grant (R01) award mechanism and runs in parallel with two FOAs of identical scientific scope, PAR-06-341 and PAR-06-342, that solicit applications under the Small Research Grant (R03) and the Exploratory/Developmental Research Grant (R21) award mechanisms, respectively. Funds Available and Anticipated Number of Awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the numbers, quality, duration, and costs of the applications received. Eligible Institutions/Organizations. Public/State Controlled Institution of Higher Education; Private Institution of Higher Education; Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education); Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education); Small Business; For-Profit Organization (Other than Small Business); State and Local Governments; U.S. Territory or Possession; Indian/Native American Tribal Government (Federally Recognized); Indian/Native American Tribal Government (Other than Federally Recognized); Indian/Native American Tribally Designated Organization; Non-domestic (non-U.S.) Entity (Foreign Organization); Hispanic-serving Institution; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); Alaska Native and Native Hawaiian Serving Institutions; Regional Organization; Others: Eligible agencies of the Federal government; Faith-based or community based organizations.